Generic
Cinnarizine
Pharmacology
Cinnarizine acts as an antihistamine, labyrinthine sedative and a peripheral antivasoconstrictor. Cinnarizine is a selective calcium antagonist, inhibiting the influx of Ca2+ intracellularly. It prevents the Ca2+ dependent contraction of arterial smooth muscle by inhibiting Ca2+ influx through smooth muscle calcium channels and thereby, improves vestibular symptoms and prevents peripheral arterial disease
Dosage Administration
Usual adult dose: 15 to 30 mg three times daily. Children (5 to 12 years): Half of the adult dose. Motion sickness: A dose of 30 mg two hours before the start of the journey and 15 mg every 8 hours during the journey. Peripheral arterial diseases: 75 mg two or three times daily.
Contraindications
The safety of Cinnarizine in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. Therefore, it is not advisable to administer Cinnarizine in pregnancy
Side Effects
Cinnarizine may cause drowsiness; patients affected in this way should not drive or operate machinery. Avoid alcoholic drink.
Pregnancy And Lactation
Anti vertigo drugs
Over The Counter Products
