Trocer
Topical Spray
Incepta Pharmaceuticals Ltd.Generic:
NitroglycerinWeight:
400 mcg/spraybest Price:
? 250.00Generic
Nitroglycerin
Indications
Nitroglycerin sublingual spray is indicated for acute relief of an attack or prophylaxis of angina pectoris due to coronary artery disease.
Pharmacology
Nitroglycerin, an organic nitrate, is a vasodilator which has effects on both arteries and veins. This is a metered dose spray containing nitroglycerin. This product delivers nitroglycerin (400 mcg per spray, 200 metered sprays) in the form of spray droplets under the tongue.
Contraindications
Use of alcohol with Nitroglycerin may produce severe hypotension and collapse. Oral Nitroglycerin may enhance the bioavailability of dihydroergotamine. Orthostatic hypotension may occur with the combined use of calcium channel blocker, phenothiazines and tricyclic antidepressants.
Side Effects
Hypersensitivity to nitrates or any constituents of the formulation. Hypotension, hypovolaemia, severe anaemia, cerebral haemorrhage and brain trauma, mitral stenosis and angina caused by hypertrophic obstructive cardiomyopathy. Concomitant administration of phosphodiesterase inhibitors used for the treatment of erectile dysfunction.
Pregnancy And Lactation
A number of nitrate related adverse effects may occur including headache, facial flushing, dizziness, nausea, vomiting, feelings of weakness, postural hypotension and reflex tachycardia .
Therapeutic
The use of Nitroglycerin during the early days of acute myocardial infarction requires particular attention to monitoring hemodynamics and clinical status. Nitroglycerin should be used with caution in patients with severely impaired renal or hepatic function, hypothyroidism, malnutrition or hypothermia.
Storage Conditions
Safety and effectiveness of nitroglycerin in pediatric patients have not been established.
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