Retrovir
Tablet
Pharmasia LimitedGeneric:
Tenofovir Disoproxil FumarateWeight:
300 mgbest Price:
? 85.00Generic
Tenofovir Disoproxil Fumarate
Contraindications
Co-administration with other drugs: Tenofovir should not be administered concurrently with Emtricitabine & Tenofovir combination or Adefovir Dipivoxil. Lactic Acidosis & Severe Hepatomegaly with Steatosis: Though the risk of occurrence of lactic acidosis is low for Tenofovir, treatment should be suspended in any patient who develops lactic acidosis or hepatotoxicity. Exacerbation of hepatitis after discontinuation of treatment: Discontinuation of Tenofovir therapy may be associated with severe acute exacerbation of hepatitis.
Side Effects
Pediatric use: Safety and effectiveness of Tenofovir in pediatric patients below the age of 18 years have not been established. Geriatrics use: Clinical studies of Tenofovir did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently from younger subjects. But care should be taken in dose selection, and it may be useful to monitor renal function. Renal Impairment: Haemodialysis patients: 300 mg once every 7 days or after a cumulative total of 12 hr of dialysis. CrCl (10-29 mL/min): 300 mg 72-96 hrly. CrCl (30-49 mL/min): 300 mg 48 hrly. Hepatic impairment: No dose adjustment is required in patients with hepatic impairment.
Pregnancy And Lactation
There is no experience of Tenofovir overdose reported in patients
Therapeutic
Drugs for HIV / Anti-retroviral drugs, Hepatic viral infections (Hepatitis B)
Storage Conditions
Drugs for HIV / Anti-retroviral drugs, Hepatic viral infections (Hepatitis B)