Generic
Oxytetracycline
Pharmacology
Oxytetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels in the bacterial membrane.
Contraindications
Results of animal studies indicate that tetracyclines cross the placenta, are found in fetal tissues and can have toxic effects on the developing fetus. Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. Tetracyclines are present in the milk of lactating women who are taking a drug in this class.
Side Effects
Oxytetracycline should be used with caution in renal impairment.
Pregnancy And Lactation
Eye Anti-Infectives & Antiseptics, Tetracycline group of drugs, Topical antibiotics for Acne
Therapeutic
Oxytetracycline should be used with caution in renal impairment.
Storage Conditions
Eye Anti-Infectives & Antiseptics, Tetracycline group of drugs, Topical antibiotics for Acne
Over The Counter Products
