Panamox
Oral Suspension
Jayson Pharmaceuticals Ltd.Generic:
MebendazoleWeight:
100 mg/5 mlbest Price:
? 14.79Generic
Mebendazole
Indications
Mebendazole is indicated for the treatment of threadworms, whipworms, roundworms and hookworms.
Pharmacology
Mebendazole is a synthetic broad-spectrum anthelmintic that is active against most nematodes and some other worms. Mebendazole is principally used in the treatment of intestinal nematode infection. Mebendazole inhibits the formation of the worms' microtubules and causes the worms' glucose depletion. After oral administration about 2-10% of oral dose is absorbed from Gl tract and peak plasma concentration occurs within 30 minutes to 7 hours. Mebendazole is highly bound to plasma protein. Elimination half-life is 2.8 to 9 hours.
Dosage Administration
Adult and Child over 2 years- Threadworms: 100 mg or 1 teaspoonful: Single dose. Whipworms, Roundworms, Hookworms: 100 mg or 1 teaspoonful: Twice daily for 3 days. If reinfection occurs the second dose may be needed after 2 weeks.
Contraindications
Mebendazole is contraindicated in patients with known hypersensitivity to Mebendazole, or to any component of the formulation.
Side Effects
Gastrointestinal: Transient symptoms of abdominal pain and diarrhoea in case of massive infection and expulsion of worms. Hypersensitivity: Rash, urticaria and angioedema have been observed on rare occasions. Central Nervous System: Very rare cases of convulsions have been reported. Haematologic: Neutropenia and agranulocytosis.
Pregnancy And Lactation
Mebendazole is not recommended in pregnant women. It is not known whether mebendazole is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when it is administered to a nursing mother.
Therapeutic
In the event of accidental overdosage, gastrointestinal complaints lasting up to a few hours may occur. Vomiting and purging should be induced.
Storage Conditions
Store in a cool (Below 25�C temperature) and dry place, protected from light. Keep out of the reach of children.
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