Labpan Tablet (Enteric Coated)
Tablet (Enteric Coated)
Labaid Pharma Ltd.Generic:
Pantoprazole Sodium SesquihydrateWeight:
20 mgbest Price:
৳ 5.00Generic
Pantoprazole Sodium Sesquihydrate
Indications
Pantoprazole is indicated where suppression of acid secretion has therapeutic benefit; i.e Peptic ulcer diseases Gastroesophageal reflux diseases Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs) Eradication of Helicobacter pylori (in combination with antibiotics) Zollinger-Ellison Syndrome
Pharmacology
Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus that persists longer than 24 hours.
Contraindications
No significant drug interactions have been observed in clinical studies.
Side Effects
Patients should be cautioned that Pantoprazole tablet should not be split, chewed or crushed. Long-term therapy of Pantoprazole may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis related disorders.
Pregnancy And Lactation
Pantoprazole is well tolerated in both short-term and long-term treatment. Headache and diarrhea are the common side effects and rarely included side effects are abdominal pain, flatulence, rash, insomnia and hyperglycemia.
Therapeutic
Proton Pump Inhibitor
Storage Conditions
Direction for use of IV injection: Pantoprazole lyophilized powder and 0.9% Sodium Chloride Injection is for intravenous administration only and must not be given by any other route. Pantoprazole IV injection should be given as a slow intravenous injection. The solution for IV injection is obtained by adding 10 ml 0.9% Sodium Chloride Injection to the vial containing powder. After reconstitution the injection should be given slowly over a period of at least 2 to 5 minutes. Use only freshly prepared solution. The reconstituted solution may be stored at room temperature (up to 30° C) for a maximum 4 hours. Direction for use of IV infusion: Pantoprazole IV infusion should be given as an intravenous infusion over a period of approximately 15 minutes. Pantoprazole IV infusion should be reconstituted with 10 ml of 0.9% Sodium Chloride Injection and further diluted (admixed) with 0.9% Sodium Chloride Injection or 5% Dextrose or Lactated Ringer's Injection to a final volume of 100 ml. The reconstituted solution may be stored at room temperature (up to 30° C) for a maximum 4 hours prior to further dilution. The admixed solution may be stored at room temperature (up to 30° C) and must be used within 24 hours from the time of initial reconstitution.
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