Generic
Protamine Crystallised Insulin Aspart
Pharmacology
Each ml solution contains 100 IU (equivalent to 3.50 mg) Insulin Aspart (rDNA).
Dosage Administration
The primary activity of Insulin Aspart is the regulation of glucose metabolism. Insulin Aspart bind to the insulin receptors on muscle and fat cells and lower blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the liver.
Contraindications
Instructions to be given to the patient before injecting this Insulin: According to the instruction given with ConviPen, insert the cartridge into the pen correctly & equip the needle Gently turn the pen upside down for 8-10 times until the insulin in the cartridge becomes uniformly mixed suspension Remove the needle cap, discharge air bubbles in the catridge Adjust the dosage button to get correct dose & inject to the specific site In order to avoid cross contamination, do not let the needle touch anything during the process of preparation.
Side Effects
Instructions to be given to the patient before injecting this Insulin: According to the instruction given with ConviPen, insert the cartridge into the pen correctly & equip the needle Gently turn the pen upside down for 8-10 times until the insulin in the cartridge becomes uniformly mixed suspension Remove the needle cap, discharge air bubbles in the catridge Adjust the dosage button to get correct dose & inject to the specific site In order to avoid cross contamination, do not let the needle touch anything during the process of preparation.
Pregnancy And Lactation
A number of drugs affect glucose metabolism and may require dose adjustment. The following substances may reduce the Insulin as well as Insulin Aspart requirements: Oral anti-diabetic products, angiotensin converting enzyme (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, pentoxifylline, salicylates and sulfonamide antibiotics. The following substances may increase the Insulin as well as Insulin Aspart requirements: Thiazides, glucocorticoids, thyroid hormones, beta-sympathomimetics, growth hormone and danazol. Beta-blockers, clonidine, lithium salts, and alcohol may either potentiate or weaken the blood glucose lowering effect of insulin.
Therapeutic
Pregnancy category B. There are no restrictions on treatment with Protamine Crystallised Insulin Aspart during lactation. Insulin treatment of the nursing mother should not affect the baby. However, dosage may need to be adjusted.
Storage Conditions
Dose adjustment and monitoring: Blood glucose should be monitored in all patients treated with insulin. Insulin regimens should be modified cautiously and only under medical supervision
Over The Counter Products
