G-Atropine
Ophthalmic Solution
Gonoshasthaya Pharma Ltd.Generic:
Atropine SulfateWeight:
1%best Price:
? 27.33Generic
Atropine Sulfate
Pharmacology
Atropine binds to and inhibit muscarinic acetylcholine receptors, producing a wide range of anticholinergic effects. Atropine is an anticholinergic agent which competitively blocks the muscarinic receptors in peripheral tissues such as the heart, intestines, bronchial muscles, iris and secretory glands. Some central stimulation may occur. Atropine abolishes bradycardia and reduces heart block due to vagal activity. Smooth muscles in the bronchi and gut are relaxed while glandular secretions are reduced. It also has mydriatic and cycloplegic effect.
Dosage Administration
Adult: IV: Bradycardia: 500 mcg every 3-5 mins. Total: 3 mg. IV/IM: Organophosphorus poisoning: 2 mg every 10-30 mins until muscarinic effects disappear or atropine toxicity appears. IM/SC: Premedication in anesthesia: 300-600 mcg 30-60 mins before anesthesia. IV/IM/SC: Poisoning or overdosage with compound having muscarinic actions: 0.6-1 mg, repeat 2 hrly. Ophthalmic: Inflammatory eye disorders: As 0.5-1% solution: 1-2 drops 4 times/day. Ophthalmic: refraction: 1% solution 1 drop twice daily for 1-2 days before procedure. Oral: Non ulcer dyspepsia, Irritable bowel syndrome, Diverticular disease: 0.6-1.2 mg as a single dose at bedtime. Usual Pediatric Dose for Anesthesia: 7 to 16 pounds: 0.1 mg, IV, IM, or subcutaneously 17 to 24 pounds: 0.15 mg, IV, IM, or subcutaneously 24 to 40 pounds: 0.2 mg, IV, IM, or subcutaneously 40 to 65 pounds: 0.3 mg, IV, IM, or subcutaneously 65 to 90 pounds: 0.4 mg, IV, IM, or subcutaneously Over 90 pounds: 0.4 to 0.6 mg, IV, IM, or subcutaneously
Contraindications
Pregnancy Category C. Animal reproduction studies have not been conducted with atropine. It also is not known whether atropine can cause fetal harm when given to a pregnant woman or can affect reproduction capacity. Atropine should be given to a pregnant woman only if clearly needed.
Side Effects
Reflux oesophagitis; elderly; infants and children; Pregnancy.
Pregnancy And Lactation
May cause hyperthermia, hypertension, increased respiratory rate, nausea and vomiting. May also lead to CNS stimulation. Severe intoxication may lead to CNS depression, coma, respiratory failure and death.
Therapeutic
May cause hyperthermia, hypertension, increased respiratory rate, nausea and vomiting. May also lead to CNS stimulation. Severe intoxication may lead to CNS depression, coma, respiratory failure and death.
Storage Conditions
Anticholinergics (antimuscarinics)/ Anti-spasmodics, Mydriatic and Cycloplegic agents
Over The Counter Products
