Floxalone Tablet
Tablet
Drug International Ltd.Generic:
Moxifloxacin HydrochlorideWeight:
400 mgbest Price:
৳ 35.00Generic
Moxifloxacin Hydrochloride
Pharmacology
Moxifloxacin is a 4th generation synthetic broad spectrum, fluoroquinolone class of antibacterial drug. It has activity against a wide range of gram-positive, gram-negative, anaerobic and atypical bacteria including Mycoplasma pneumoniae. It acts by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV which are necessary for bacterial DNA replication, transcription & repair.
Dosage Administration
Acute bacterial sinusitis: 400 mg once daily 7-10 days. Acute bacterial exacerbation of chronic bronchitis: 400 mg once daily 5-10 days. Community-acquired pneumonia: 400 mg once daily 7-14 days. Uncomplicated skin and skin structure infections: 400 mg once daily 7 days. Complicated skin and skin structure infections: 400 mg once daily 7-21 days. Complicated intra-abdominal infections: 400 mg once daily 5-14 days. Pelvic inflammatory disease: 400 mg once daily 14 days.
Contraindications
US FDA pregnancy category C. Moxifloxacin is not recommended during pregnancy & lactation.
Side Effects
Moxifloxacin may cause an increased risk of tendinitis and tendon rupture. It should be discontinued if pain or inflammation in a tendon occurs. It should not be used in patients with known prolongation of the QT interval, patients with uncorrected hypokalemia, and patients with receiving Class IA or Class III antiarrhythmic agents
Pregnancy And Lactation
Renal or hepatic impaired patients: No dose adjustment is necessary for patients with renal or hepatic impairment. Pediatric patients: Safety and effectiveness of Moxifloxacin in pediatric patients and adolescent less than 18 years of age have not been established.
Therapeutic
4-Quinolone preparations
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.