Emaprox Tablet (Delayed Release)
Tablet (Delayed Release)
Globe Pharmaceuticals Ltd.Weight:
375 mg+20 mgbest Price:
৳ 8.00Generic
Naproxen Sodium + Esomeprazole Magnesium
Indications
Naproxen & Esomeprazole is indicated for the relief of signs & symptoms of- Osteoarthritis Rheumatoid arthritis Ankylosing spondylitis & To decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.
Side Effects
With medicine: Concomitant use of NSAIDs may reduce the antihypertensive effect of ACE inhibitors, diuretics & beta-blockers Concomitant use of this tablet and warfarin may result in an increased risk of a bleeding complication. Esomeprazole inhibits gastric acid secretion & may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (eg. Ketoconazole, iron salts and digoxin). With food & others: Administration of Naproxen & Esomeprazole together with high-fat food in healthy volunteers does not affect the extent of absorption of naproxen but significantly prolongs tmax by 10 hours and decreases peak plasma concentration (Cmax) by about 12%
Pregnancy And Lactation
Do not split, chew, crush or dissolve the tablet. This tablet is to be taken at least 30 minutes before meals.
Therapeutic
Patients with known CV disease/risk factors may be at greater risk. This tablet should be used with caution in patients with fluid retention or heart failure.
Storage Conditions
With medicine: Concomitant use of NSAIDs may reduce the antihypertensive effect of ACE inhibitors, diuretics & beta-blockers Concomitant use of this tablet and warfarin may result in an increased risk of a bleeding complication. Esomeprazole inhibits gastric acid secretion & may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (eg. Ketoconazole, iron salts and digoxin). With food & others: Administration of Naproxen & Esomeprazole together with high-fat food in healthy volunteers does not affect the extent of absorption of naproxen but significantly prolongs tmax by 10 hours and decreases peak plasma concentration (Cmax) by about 12%