Efirel
Tablet
Opsonin Pharma Ltd.Generic:
Prasugrel HydrochlorideWeight:
10 mgbest Price:
? 20.00Generic
Prasugrel Hydrochloride
Indications
Prasugrel is indicated to reduce the rate of thrombotic cardiovascular (CV) events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI) as follows: Patients with unstable angina (UA) or non-ST-elevation myocardial infarction (NSTEMI). ... Read morePrasugrel is indicated to reduce the rate of thrombotic cardiovascular (CV) events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI) as follows: Patients with unstable angina (UA) or non-ST-elevation myocardial infarction (NSTEMI). Patients with ST-elevation myocardial infarction (STEMI) when managed with primary or delayed PCI.
Pharmacology
Prasugrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets.
Dosage Administration
Treatment should be initiated with a single 60 mg oral loading dose. Continue at 10 mg once daily with or without food. Consider 5 mg once daily for patients <60 kg. Patients should also take aspirin (75 mg to 325 mg) daily.
Contraindications
Active pathological bleeding such as peptic ulcer or intracranial haemorrhage. Patient with a history of prior transient ischemic attack or stroke
Side Effects
Bleeding Thrombotic thrombocytopenic purpura Other side effects (Headache, back pain, dyspnea, nausea, hypertension, bradycardia, rash etc)
Pregnancy And Lactation
There are no adequate and well-controlled studies of Prasugrel use in pregnant women. Reproductive and developmental toxicology studies in rats and rabbits at doses of up to 30 times the recommended therapeutic exposures in humans revealed no evidence of fetal harm; however, animal studies are not always predictive of a human response. It is not known whether Prasugrel is excreted in human milk. Because many drugs are excreted in human milk, Prasugrel should be used during nursing only if the potential benefit to the mother justifies the potential risk to the nursing infant.
Therapeutic
Anti-platelet drugs
Storage Conditions
Anti-platelet drugs
Over The Counter Products
