Doxorubicin HEXAL
IV Infusion
SANDOZ (A Novartis Division)Generic:
Doxorubicin HydrochlorideWeight:
2 mg/mlbest Price:
? 540.27Generic
Doxorubicin Hydrochloride
Contraindications
Leucopenia, thrombocytopenia, nausea, vomiting, diarrhoea. Rarely facial flushing, rash, alopecia. Blurred vision, headache, seizures, paraesthesia, confusion, malaise, lethargy, skin pigmentation.
Side Effects
Acute overdosage may increase the toxic effects of mucositis, leukopenia and thrombocytopenia. Treatment includes hospitalisation of the severely myelosuppressed patient, antimicrobials, platelet transfusions and symptomatic treatment of mucositis. Use of haemopoietic growth factor (G-CSF, GM-CSF) may be considered. Cumulative dosage increases risk of cardiomyopathy and resultant congestive heart failure which may be managed with digitalis preparations, diuretics, and after load reducers such as ACE inhibitors.
Pregnancy And Lactation
Elderly, children, hepatic impairment. Monitor blood counts and ECG.
Therapeutic
Cytotoxic Chemotherapy
Storage Conditions
Powder for injection: Store at 15-30�C. Solution for injection & liposomal formulations: Refrigerate at 2-8�C. Do not freeze.
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