Doxibac Capsule
Capsule
Popular Pharmaceuticals Ltd.Generic:
Doxycycline HydrochlorideWeight:
100 mgbest Price:
৳ 2.50Generic
Doxycycline Hydrochloride
Indications
Doxycycline Hydrochloride is indicated in the following infections caused by susceptible microorganisms: Respiratory tract infections: Pneumonia, influenza, sinusitis, bronchitis, tonsillitis, tracheitis. Gastrointestinal tract infections: Cholera, traveler's diarrhea, shigella dysentery, acute intestinal amebiasis. ... Read moreDoxycycline Hydrochloride is indicated in the following infections caused by susceptible microorganisms: Respiratory tract infections: Pneumonia, influenza, sinusitis, bronchitis, tonsillitis, tracheitis. Gastrointestinal tract infections: Cholera, traveler's diarrhea, shigella dysentery, acute intestinal amebiasis. Chlamydial infections: Lympho-granuloma venereum, psittacosis, trachoma. Sexually transmitted diseases: Non gonococcal urethritis, acute pelvic inflammatory disease, uncomplicated urethral and endocervical or rectal infections, gonorrhoea, syphilis, pyelonephritis, cystitis. Other infections: Impetigo, furunculosis, inclusion conjunctivitis, brucellosis, tularemia, cellulitis, acne and Q-fever.
Pharmacology
Doxycycline is a highly active broad-spectrum antibiotic of tetracycline group. It is effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia and mycobacteria. Doxycycline is used as an alternate to penicillin in the treatment of gonorrhoea and syphilis. Doxycycline has its main mechanism of action on protein synthesis. Inside the bacterial cell, it inhibits protein synthesis.
Contraindications
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Side Effects
Nausea, vomiting, diarrhoea, skin rashes, hemolytic anaemia, eosinophilia may be reported.
Pregnancy And Lactation
Absorption of tetracyclines is impaired by antacid containing aluminium, calcium or magnesium, and iron containing preparation. Absorption of tetracyclines is also impaired by bismuth salicylate. Barbiturates, carbamazepine and phenytoin decrease half-life of doxycycline. Concurrent use of tetracyclines may render oral contraceptive less effective. Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosages. It is advisable to avoid giving tetracyclines in conjunction with penicillin.
Therapeutic
Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Storage Conditions
The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of teeth. Tetracyclines drugs, therefore should not be used in this age group.
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