Diplin Tablet
Tablet
Navana Pharmaceuticals Ltd.Generic:
LinagliptinWeight:
5 mgbest Price:
৳ 15.00Generic
Linagliptin
Pharmacology
Linagliptin is indicated to improve glycemic control in patients with type 2 diabetes mellitus. Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4), an enzyme that degrades the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide). Thus, Linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin from pancreatic beta (β) cells in a glucose-dependent manner and decreasing the secretion of glucagon from pancreatic alpha (α) cells in the circulation.
Dosage Administration
Linagliptin 5 mg once daily. If added to metformin, the dose of metformin should be maintained and linagliptin administered concomitantly. When used in combination with a sulfonylurea, a lower dose of the sulphonylurea may be considered to reduce the risk of hypoglycaemia. Patients with renal impairment: No dose adjustment required. Linagliptin can be taken with or without a meal at any time of the day.
Contraindications
Pregnancy category B. There are no adequate and well controlled studies in pregnant women. So, Linagliptin tablets should be used during pregnancy only if clearly needed. It is not known whether Linagliptin passes into breast milk or not.
Side Effects
Hypersensitivity to the active substance or to any of the excipients.
Pregnancy And Lactation
Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Therapeutic
Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
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