Devomit Tablet
Tablet
Silva Pharmaceuticals Ltd.Generic:
Meclizine + PyridoxineWeight:
25 mg+50 mgbest Price:
৳ 3.25Generic
Meclizine + Pyridoxine
Pharmacology
Meclizine is a piperazine-derivative antihistamine that is used as an antiemetic. It has antiemetic, anticholinergic and antihistaminic properties. It reduces the sensitivity of the labyrinthine apparatus. The action may be mediated through nerve pathways to the vomiting center (VC) from the chemoreceptor trigger zone (CTZ), peripheral nerve pathways, the VC, or other CNS centers. Pyridoxine is vitamin B-6. It has been added to enhance the anti-emetic effects & as a dietary suppliment.
Dosage Administration
Adult and Children 12 years of age & over: Nausea and vomiting: 25-50 mg daily or as directed by a physician. Motion sickness: Take an initial dose of 25-50 mg, 1 hour prior to travel. May repeat the dose every 24 hours for the duration of the journey. Radiation sickness: 50 mg administered 2-12 hours prior to radiation treatment. Vertigo: 25-100 mg daily in divided doses. Prevention of nausea and vomiting associated with emergency contraceptive pill (ECP): 25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours. The safety and efficacy for use in children less than 12 years of age have not been established.
Contraindications
Meclizine Hydrochloride and Pyridoxine Hydrochloride is contraindicated in patients who are hypersensitive to these ingredients.
Side Effects
Drowsiness, dry mouth and, on rare occasions, blurred vision have been reported.
Pregnancy And Lactation
Pregnancy Category B. Large-scale human studies have not demonstrated adverse fetal effects. It has been suggested that based on available data, Meclizine presents the lowest risk of teratogenicity and is the drug of first choice in treating nausea and vomiting during pregnancy. Safety for use in the nursing mother has not been established.
Therapeutic
Symptoms: Extreme excitability, seizures, drowsiness and hallucinations. Treatment: Appropriate supportive and symptomatic treatment. Consider dialysis
Storage Conditions
Anti-emetic drugs
Over The Counter Products
