Generic
Pancreatin
Pharmacology
Each enteric film-coated tablet contains 325 mg of Pancreatin BP that provides not less than the following enzymatic activity- Amylase 7800 units Protease 455 units Lipase 6500 units
Contraindications
Alkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Pancreatin should not be used concurrently with antacid.
Side Effects
Pancreatin is contraindicated in patients with known hypersensitivity to the drug.
Pregnancy And Lactation
The most frequent side effects are gastrointestinal including nausea, vomiting and abdominal discomfort. Buccal and perianal soreness may occur, particularly in infants. Hypersensitivity reactions manifested by sneezing, lacrimation or skin rashes have been reported.
Therapeutic
Patients known to be allergic to animal protein should be treated with caution.
Storage Conditions
Excessive dosage may produce a laxative effect. Systemic toxicity does not occur. Very high dosage may cause hyperuricaemia and hyperuricosuria