Generic
Ranitidine Hydrochloride
Indications
Ranitidine is indicated in: Treatment of active duodenal ulcer Benign gastric ulcer Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent Post operative stress ulcer. Zollinger-Ellison Syndrome. Gastroesophageal reflux disease (GERD). Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient. Recurrent haemorrhage in patients with bleeding peptic ulcer. Before general anesthesia in patient considered to be at risk of acid aspiration particulary obstetric patients.
Contraindications
Ranitidine should be given in reduced dosage to patients with impaired renal and hepatic function.
Side Effects
Use in elderly patients: In clinical trial the ulcer healing rates have been found similar in patients age 65 and over with those in younger patients. Additionally, there was no difference in the incidence of adverse effects.
Pregnancy And Lactation
Ranitidine is very specific in action and accordingly no particular problems are expected following overdosage with the drug. Symptomatic and supportive therapy should be given as appropriate. If required, the drug may be removed from the plasma by haemodiaiysis.
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