Azmasol Respirator Solution
Respirator Solution
Beximco Pharmaceuticals Ltd.Generic:
SalbutamolWeight:
5 mg/mlbest Price:
৳ 120.00Generic
Salbutamol
Indications
Salbutamol is indicated as a broncho dilator for use in-Asthma Chronic Bronchitis Emphysema andOther conditions associated with airways obstruction.
Pharmacology
Salbutamol is a selective β2-adrenoceptor agonist. At therapeutic doses, it acts on the β2-adrenoceptors of bronchial smooth muscle, with little or no action on the β1-adrenoceptors of cardiac muscle. Salbutamol provides short-acting (4-6 hours) bronchodilatation with a fast onset (within 5 minutes) in reversible airway obstruction. It also has an anti-inflammatory effect on mast cells causing inhibition of release of bronchoconstrictor mediators including histamine, neutrophil chemotactive factor (NCF) and prostaglandin D2.
Dosage Administration
Administer Salbutamol Inhaler by oral inhalation only. Shake Salbutamol Inhaler well before each spray. For relief of acute episodes of bronchospasm: Adults: 1 or 2 puffs as necessary. The maximum dose is up to 8 puffs in 24 hours. Children: Half the adult dose. To prevent allergen-or exercise-induced bronchospasm: Adults: 2 puffs 15 minutes prior to exercise or exposure to the allergen. The maximum dose is 2 puffs, up to 4 times a day. Children: Half the adult dose. Chronic therapy: Adults: Up to 200 mcg (2 puffs) four times daily. Children: Up to 200 mcg (2 puffs) four times daily.
Contraindications
Salbutamol should be used with caution in patients with hyperthyroidism, cardiovascular disease, occlusive vascular disorders, hypertension and aneurysms. Hypokalaemia associated with high doses of Salbutamol may result in increased susceptibility to digitalis-induced cardiac arrhythmia. Tachyphylaxis with resistance may occur with prolonged use of high dosage. Care is necessary when treating patients with diabetes mellitus or closed angle glaucoma, and in those receiving antihypertensive therapy.
Side Effects
The symptoms with overdosage are angina, headache, nausea, vomiting, tremor etc. The preferred antidote for overdosage with Salbutamol is a cardio-selective beta-blocking agent but beta-blocking drugs should be used with caution in patients with a history of bronchospasm.
Pregnancy And Lactation
Short-acting selective & β2-adrenoceptor stimulants
Over The Counter Products
