Antismin Syrup
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Silco Pharmaceutical Ltd.Generic:
Chlorpheniramine MaleateWeight:
2 mg/5 mlbest Price:
৳ 21.77Generic
Chlorpheniramine Maleate
Pharmacology
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.
Dosage Administration
Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily. Child- 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily. 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily. 1-2 years: 1 mg twice daily. Below 1 year the use of Chlorpheniramine Maleate is not recommended.
Contraindications
Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.
Side Effects
Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Pregnancy And Lactation
This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy.
Therapeutic
Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Storage Conditions
CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.
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