Anset Oral Solution
Oral Solution
Opsonin Pharma Ltd.Generic:
OndansetronWeight:
4 mg/5 mlbest Price:
৳ 45.00Generic
Ondansetron
Pharmacology
Ondansetron oral soluble film is a orally dissolving film designed to be applied on top of the tongue where it will dissolve within 20 seconds and then is swallowed with saliva. Oral soluble film does not require water to aid dissolution or swallowing. The active ingredient in this preparation is ondansetron base, the racemic form of ondansetron, and a selective blocking agent of the serotonin 5-HT3 receptor type. The empirical formula is C18H19N3O representing a molecular weight of 293.3.
Contraindications
Administration of Oral Soluble Film: Step 1: Tear the pouch carefully along with the edge tear mark. Step 2: Put the Ondansetron film on top of your tongue. It will dissolve within 20 seconds Step 3: Do not chew or swallow the film whole. Step 4: Swallow after the Onsaf oral soluble film dissolves. You may swallow the dissolved film with or without liquid. Step 5: Wash your hands after taking Onsaf oral soluble film
Pregnancy And Lactation
Ondansetron does not itself appear to induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system of the liver. Because Ondansetron is metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes, inducers or inhibitors of these enzymes may change the clearance and hence, the half-life of Ondansetron. On the basis of available data, no dosage adjustment of Ondasetron is recommended for patients on these drugs.
Therapeutic
Contraindicated in patients known to have hypersensitivity to the drug or any of its components. Concomitant use of apomorphine.
Storage Conditions
Frequently reported adverse events were headache, constipation and diarrhea, but the majority have been mild or moderate in nature. In chemotherapy-induced nausea and vomiting, rash has occurred in approximately 1% of patients receiving Ondansetron. There also have been reports to a sensation of flushing or warmth, hiccups and liver enzyme abnormalities. Rare cases of anaphylaxis, brochospasm, tachycardia, angina (chest pain), hypokalemia, shortness of breath have also been reported, except for bronchospasm and anaphylaxis, the relationship to Ondansetron is unclear. There have been no evidence to extrapyramidal reactions, in rare case oculogyric crisis appearing alone, as well as with other dystonic reactions without definitive clinical evidence. In case of PONV, with the exception of headache, rates of these events were not significantly different in the Ondansetron and placebo groups.
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