Anget MR
Tablet (Modified Release)
Orion Pharma Ltd.Generic:
Trimetazidine DihydrochlorideWeight:
35 mgbest Price:
? 6.00Generic
Trimetazidine Dihydrochloride
Pharmacology
Trimetazidine Dihydrochloride is the first 3- keto acyl CoA thiolase inhibitor (KAT), a metabolic anti-ischemic agent with proven benefits for all coronary patients. Trimetazidine Dihydrochloride inhibits fatty acid pathway by inhibiting 3-keto acyl CoA thiolase enzyme and transfers oxygen to glucose pathway. Since glucose pathway is more efficient in producing energy, the same oxygen produces more energy and makes the heart more active. Moreover, the aerobic oxidation of glucose stops production of lactic acid, which prevents angina pectoris.
Contraindications
No drug interaction so far has been reported. In particular, no interaction has been reported with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents or digitalis preparation.
Side Effects
Trimetazidine is contraindicated in patients who have hypersensitivity to the active substance or to any of the excipients. It is also is contraindicated in patients with Parkinson�s disease, parkinsonian symptoms, tremors, restless legs movement disorders, severe renal impairment.
Pregnancy And Lactation
Trimetazidine is safe and well tolerated. The Common side effects associated with Trimetazidine are dizziness, headache, abdominal pain, diarrhoea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria and asthenia
Therapeutic
Other Anti-anginal & Anti-ischaemic drugs
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
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