Generic
Naproxen Sodium
Pharmacology
Naproxen is a non steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic & antipyretic properties. It is rapidly absorbed from the gastrointestinal tract and achieves 95% bioavailability.
Contraindications
ACE inhibitors: diminish the antihypertensive effect of ACE inhibitors. Antacids & Sucralfate: delay the absorption of Naproxen. Aspirin: increase adverse effects. Diuretics: reduce the natriuretic effect of Furosemide and Thiazides. Methotrexate: enhance the toxicity of Methotrexate. Warfarin: increase the risk of GI bleeding. Selective Serotonin Reuptake Inhibitors (SSRI): increase the risk of GI bleeding.
Side Effects
Naproxen is contraindicated in patients with known hypersensitivity to Naproxen. It should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. It is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.
Pregnancy And Lactation
Most frequently reported side effects include following: Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia. Central Nervous System: Headache, vertigo, drowsiness. Dermatological: Pruritus (itching), purpura. Cardiovascular: Edema, palpitation. Others: Visual disturbances, hearing disturbances.
Therapeutic
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
Over The Counter Products
