Alucil-S Chewable Tablet
Lotion
Square Pharmaceuticals Ltd.Generic:
IvermectinWeight:
0.005best Price:
৳ 130.00Generic
Ivermectin
Indications
Ivermectin is indicated for topical treatment of head lice infestations in patients 6 months of age and older.
Pharmacology
Ivermectin, a member of the avermectin class, causes death of parasites, primarily through binding selectively and with high affinity to glutamate-gated chloride channels, which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligandgated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The selective activity of compounds of this class is attributable to the fact that some mammals do not have glutamate-gated chloride channels, the avermectins have a low affinity for mammalian ligand-gated chloride channels, and Ivermectin does not readily cross the blood-brain barrier in humans.
Dosage Administration
Only for topical use in scalp & scalp hair. It is not for oral, ophthalmic or intravaginal use. Apply the Lotion to dry hair in an amount sufficient (up to 1 tube) to thoroughly coat the hair and scalp. After 10 minutes, rinse off with water. The tube is intended for single use. Discard any unused portion. Contact with eyes should be avoided
Side Effects
Common side effects are- Conjunctivitis Ocular hyperemia Eye irritation Dandruff Dry skin Skin burning sensation etc.
Pregnancy And Lactation
Pregnancy Category C. There are no adequate and well-controlled studies with Ivermectin Lotion in pregnant women. Ivermectin Lotion should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Following oral administration, Ivermectin is excreted in human milk in low concentrations. This has not been evaluated following topical administration. Caution should be exercised when Ivermectin Lotion is administered to a nursing woman.
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