AFM Ophthalmic Suspension
Tablet
Albion Laboratories LimitedGeneric:
Flupentixol + MelitracenWeight:
0.5 mg+10 mgbest Price:
৳ 3.50Generic
Flupentixol + Melitracen
Pharmacology
This consists of two well known and well proven compounds: flupentixol-a neuroleptic with anxiolytic and antidepressant properties of its own when given in small doses, and melitracen-a bipolar thymoleptic with activating properties in low doses. In combination the compounds render a preparation with antidepressant, anxiolytic and activating properties. Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and in about 4 hours after oral administration of melitracen. The biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours. The combination of flupentixol and melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.
Dosage Administration
Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets. Elderly patients: 1 tablet in the morning. Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.
Contraindications
The immediate recovery phase after myocardial infarction. Defects in bundle-branch conduction. Untreated narrow-angle glaucoma. Acute alcohol, barbiturate and opiate intoxications. This tablet should not be given to patients who have received an MAO-inhibitor within two weeks. Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics.
Side Effects
In the recommended doses side effects are rare. These could be transient restlessness and insomnia.
Pregnancy And Lactation
This tablet should preferably not be given during pregnancy and lactation.
Therapeutic
Combined anxiolytics & anti-depressant drugs
Storage Conditions
Store at a temperature not exceeding 30°C in a dry place. Protect from light. Keep out of reach of children.
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