G-Vitamin B1 Tablet
Tablet
Gonoshasthaya Pharma Ltd.Generic:
Thiamine HydrochlorideWeight:
100 mgbest Price:
৳ 60.00Generic
Thiamine Hydrochloride
Indications
Thiamine is specifically used in the treatment of the various manifestations of thiamine deficiency such as Beriberi and Wernick's encephalopathy, neuritis associated with pregnancy and pellagra. Supplementary Thiamine may be indicated prophylactically in conditions where there is low dietary intake or impaired gastro intestinal absorption of thiamine (e.g. alcohol) or where requirements are increased (pregnancy, carbohydrate rich diet).
Pharmacology
Thiamine, in the form of thiamine pyrophosphate, is the coenzyme for decarboxylation of α-ketoglutaric acid. Thiamine deficiency affects the peripheral nervous system, the gastrointestinal tract, and the cardiovascular system. This vitamin is necessary for the optimal growth of infants and children. Thiamine is not stored in the body, and is regularly lost from tissues during short periods of deficiency. In order to maintain normal health, an adequate amount of thiamine is required every day. Deficiency of thiamine leads to fatigue, anorexia, gastrointestinal disturbance, tachycardia, irritability and neurological symptoms. Beriberi, a disease due to vitamin B1 deficiency, is common in alcoholics, in pregnant women receiving an inadequate diet, and in people with malabsorption syndrome, prolonged diarrhoea and hepatic disease. Thiamine is well absorbed from the gastrointestinal tract and widely distributed throughout the body. Thiamine is rapidly absorbed from the upper small intestine. Thiamine is not stored in the body to any appreciable extent. Excess ingested thiamine appears in urine as intact thiamine or as pyrimidine, which arises from degradation of the thiamine molecule. The plasma half life of thiamine is 24 hours.
Dosage Administration
Prophylaxis: 3 to 10 mg daily. Mild chronic deficiency: 10 to 25 mg daily. Severe deficiency: 200 to 300 mg daily.
Contraindications
The drug may be given safely to neonates, children, pregnant and lactating women and elderly patients.
Side Effects
Vitamin-B preparations
Pregnancy And Lactation
Thiamine injection should be protected from light and moisture.
Therapeutic
Thiamine injection should be protected from light and moisture.
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